DEVIL'S CLAW 510MG 100CAPS | PURITAN'S PRIDE

Devils Claw 510mg 100caps | Puritans Pride
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Herb traditionally used to promote joint flexibility
Also known as grapple root or wood spider
A traditional favorite in Africa and Europe
Devils Claw, a traditional joint-supporting herb, has been used in Africa and Europe for more than 350 years as an herb for flexibility. Puritans Pride Devils Claw delivers 510 mg of this effective herb in every capsule.

Supplement Facts

Serving Size 3 Capsules
Servings Per Container 33
Amount Per Serving % Daily Value
Total Carbohydrate <1 g <1%*
Devil’s Claw 1,530 mg (1.53g) **
(Harpagophytum procumbens) (root)
*Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value not established.
Directions: For adults, take three (3) capsules three times daily, preferably with meals. Capsules may be opened and prepared as a tea.

Other Ingredients: Gelatin, Vegetable Magnesium Stearate, Silica.

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Not intended for use by persons under the age of 18. Keep out of reach of children. Store at room temperature. Do not use if seal under cap is broken or missing.

BENEFITS OF THE PRODUCT

Devils Claw, Harpagophylum Procumbens, is a South African plant. Devils claw thrives in clay or sandy soils. Devils Claw root is collected when the rainy season ends. Devils Claw fruits seem to be covered with miniature grappling hooks. Synonyms include wood spider and grapple plant. German called it Teufelskralle.

Devils Claw roots are traditionally used for various conditions: liver disease, kidney disease, bladder disease, allergies, arteriosclerosis, gastrointestinal disturbances, menstrual difficulties, neuralgia, headache, fevers, indigestion, nicotine poisoning, rheumatism and arthritis.

Devils claw benefits - anti-oxidative effects

According to a Trolox equivalent antioxidant capacity assay, Devils Claw extract was particularly rich in water-soluble antioxidants.

Devils claw benefits - anti-inflammatory effects

In 1997, an experiment demonstrated the anti-inflammatory effects of Devils Claw. In 2001, Devils Claw extract was shown to prevent the LPS-induced synthesis of tumour necrosis factor alpha (TNFalpha) in stimulated primary human monocytes in a dose-dependent manner. Primary human monocyte has been used as a model for peripheral inflammation. Thus, this model suggested that Devils Claw extract might have anti-inflammatory properties on skeletal system. Nowadays, it is believed that Devils Claw Extract may offer benefits on inflammatory conditions such asarthritis, rheumatism, acne skin allergy and ulcers.

Devils Claw benefits - analgesic effects

Studies demonstrated the analgesic effects of Devils Claw . The main irridoid glycoside of Devils Claw appear to play an important role in the peripheral analgesic activites.

Devils Claw Benefits - anti-cancer effects

Numerous anti-inflammatory agents have been shown to exert chemopreventive activity by targeting cyclooxygenase (COX)-2, a rate-limiting enzyme involved in the inflammatory process. Topical application of Devils Claw extracts inhibited TPA-induced COX-2 expression in mouse skin. Devils Claw extracts diminished TPA-stimulated catalytic activity of extracellular signal-regulated protein kinase (ERK), which is known to regulate the activation of eukaryotic transcription factors mediating COX-2 induction.

Devils Claw Benefits - on osteoarthritis

It is known that Devils Claw extracts has anti-inflammatory and analgesic properties, thus, Devils Clow benefits on osteoarthritis are expected.

Devils Claw benefits - on diabetes

Devils Claw root (dosage 50-800 mg/kg i.p.) produced dose-dependent, significant reductions in the blood glucose concentrations of both fasted normal and fasted diabetic rats. The results of this experimental animal study indicate that Devils Claw root aqueous extract possesses hypoglycaemic properties. Scientists even suggest to develop a therapeutics using purified Devils Claw extracts to manage type-2 diabetes mellitus.

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