VITAMIN B1 + B6 + B12 VITACORE 100 MG/ 100 MG/ 1 MG PER 3ML.

VITAMIN B1 + B6 + B12
VITACORE
100 mg/ 100 mg/ 1 mg per 3ml.

Solution for Injection (IM)
Each 3ml solution (1 ampoule) contains:
Thiamine HCI (Vitamin B1)…………….…. 100mg
Pyridoxine HCI (Vitamin B6)……………... 100mg
Cyanocobalamin (Vitamin B12)……………..1mg

DESCRIPTION:
A clear red liquid

INDICATIONS:
Neurological diseases caused by severe vitamin B1,B6 and B12 deficiencies that cannot be remedied by means of oral theraphy.

DOSAGE AND ADMINISTRATIONS:
Vitamin B1 + B6 + B12 solution for injection are to be administered intramuscularly ( by deep intragluteal injection).
In severe (acute) cases: One ampoule daily until the acute symptoms subside.
After improvement of symptoms: One ampoule 1-3 times per week.

CONTRADICTION:
Hypersensitivity to the active substances or to any of the excipients
SPECIAL WARNINGS AND PRECAUTIONS:
Vitamin B1 + B6 + B12 Solution for Injection must not be administered by intravenous injection.

Short-term parenteral vitamin B12 administration may temporarily impair the diagnosis funicular myelosis oe pernicious anemia.
If symptoms of peripheral sensory neuropathy (paraesthesia) occur, the dosage should be reviewed and treatment with the medicinal product discontinued, if necessary. Neuropathies have been observed under long-term administration (over 2 months) of more than 1g vitamin B6 per day.

Vitamin B1 + B6 + B12 Solution for Injection may be used in children and adolescents only in the case of compelling reasons.

Each ampoule contains 42 mg sodium. This is to be taken into account in persons under sodium-restricted diet (low in table salt/sodium).

Each ampoule contains traces of potassium.

INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION
Thiamine is inactivated by fluorouracil as the latter competitively inhibits the phosphorylation of thiamine to thiamine pyrophosphate.
Loop diuretics, e.g. furosemide that inhibit tubular reabsorption may cause increased excretion of thiamine in long-term therapy and thus, lowering of the thiamine level.
If taken simultaneous administration of pyridoxine antagonists (e.g. isoniazide (INH), hydralazine, D-penicillamine or cycloserine) may increase the vitamin B6 requirement.
Beverages containing sulphite (e.g. wine) enhance thiamine degradation.

PREGNANCY AND LACTATION:
Pregnancy
There are only insufficient animal studies on the effect of this medicinal product on pregnancy, embryo-foetal, prenatal and postnatal development. The possible risk for human beings is not known. The treating physician should decide about the use of this product during pregnancy after carefully weighing the risk-to-benefit ratio.
Lactation

Vitamins B1, B6 and B12 are secreted into human breast milk. High concentrations of vitamin B6 can inhibit the production of breast milk. Data on the extent of secretion into breast milk from animal studies are not available. Therefore, the advantages of breast-feeding for the infant should be carefully weighed against the therapeutic benefit for the women in order to decide to either discontinue breast-feeding or therapy with Vitamin B1 + B6 + B12 Solution for Injection.

UNDESIRABLE EFFECTS
Nervous System disorders:
Unknown Long-Term intake (> 6-12 months) of a daily dosage > 50 mg vitamin B6 may cause peripheral sensory neuropathy.

Gastrointestinal disorders:
Unknown: Gastrointestinal complaints such as nausea, vomiting, diarrhea and abdominal pain.

Immune system disorders:
Very rare: Hypersensitivity reactions such as sweating, tachycardia and skin reactions like itching and urticaria, as well as anaphylaxis.

Skin and subcutaneous tissue disorders:
Unknown: Allergic reactions, eczematous skin alterations and a benign form of acne have been observed after high-dose vitamin B12

General disorders and administration site conditions:
Unknown: Injection-site reactions.

Imported and distributed:
GreenCore Pharma Inc.
Room 319, Pacific Land and Building
460Quintin Paredes St. Binondo Manila Philippines

Manufactured by:
FUREN PHARMACEUTICAL GROUP CO., LTD

Xuanwu Economic Developing Area,
Luyi Country, Henan, China

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DUROMINE 30mg Ph2500 30capsules


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TATIONIL by Teofarma, Italy made (10x600mg) Php 2,600 / box FREE VITAMIN C
SALUTA by Asiapharm (Singapore) PTE Ltd. (10x600mg) Php1950 /box FREE VITAMIN C
TAD by Biomedica Foscama, Italy made (10x600mg) Php 2,200 / box FREE VITAMIN C
GLUTAX 5GS Micro (6 vials x 5000mg gluta w vit c, vit e, and collagen) Php 2,000
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GLUTAX 500GS (10 vials, 20 ampoules) Php 3300
GLUTAX 2000S (10 vials) Php3300

Vitamin-C Injectables:
Laroscorbine w/ Collagen by Roche (10x5ml) Php 1800 / box
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Other Injectables:
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topical anesthesia 10.56% lidocaine and 2.56% prilocaine:
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Call or text us:
GLOBE: 0916-301-3870
GLOBE: 0917-851-5158
SMART: 0928-703-1532
SUN: 0932-884-3568
SUN : 0925-664-0211